Occult cancer screening in patients with venous thromboembolism: guidance from the SSC of the ISTH

Resumen:
Venous thromboembolism (VTE) can be the first manifestation of cancer. Although four prospective studies have suggested that limited occult cancer screening might be adequate after a first unprovoked VTE 1-4, there is no evidence that it should be applied to all VTE patients (provoked events, unusual site VTE, etc.). Furthermore, other uncertainties, such as which tests should be performed or whether occult cancer screening should be performed after a recurrent VTE event, still remain. Our objective is to provide guidance on the different management options for clinicians facing these frequent challenges.